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This meeting took place in 2019
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Obesity and Adipose Tissue Biology (J7)
Organizer(s) Matthias Blüher, Philipp E. Scherer and Anne Bouloumié
February 10—14, 2019
Fairmont Banff Springs • Banff, Alberta Canada
Discounted Abstract Deadline: Oct 23, 2018
Abstract Deadline: Nov 8, 2018
Scholarship Deadline: Oct 23, 2018
Discounted Registration Deadline: Dec 11, 2018
Sponsored by Bayer AG, MedImmune and Novo Nordisk A/S
This activity is also supported by an educational grant from Lilly
This activity is also supported by an educational grant from Lilly
Summary of Meeting:
Obesity is a growing worldwide epidemic, increasing co-morbid conditions, such as diabetes. The joint conferences on “Obesity and Adipose Tissue Biology” and “Functional Neurocircuitry of Feeding and Feeding Disorders” are aimed to foster cross-talk between these research areas. Adipose tissue is an endocrine organ that is both controlled by and sends signals to the brain and other organs. In addition, obesity causes an inflammatory state in the adipose tissue. The recognition that brown/beige adipose tissue is active in adult humans has triggered interest in understanding the physiology and relative importance of these tissues. Exercise and bariatric surgery are known to elicit profound metabolic benefits in type 2 diabetes, although the underlying mechanisms remain unclear. This conference will bring together cell biologists, biochemists, geneticists, physiologists, drug developers and clinical researchers, thereby facilitating knowledge exchange and interactions leading to elucidation of better treatments for obesity and diabetes. Specifically, it will examine recent advances in our understanding of brown/beige adipose tissue function; obesity-induced adipose inflammation; control of adipose tissue, appetite and energy metabolism; endocrine and paracrine signaling via secreted factors; molecular mechanisms of metabolic signaling; emerging topics, including long noncoding RNA and the gut microbiome; and approaches to drug development and the treatment of obesity and diabetes.
View Scholarships/Awards
Obesity is a growing worldwide epidemic, increasing co-morbid conditions, such as diabetes. The joint conferences on “Obesity and Adipose Tissue Biology” and “Functional Neurocircuitry of Feeding and Feeding Disorders” are aimed to foster cross-talk between these research areas. Adipose tissue is an endocrine organ that is both controlled by and sends signals to the brain and other organs. In addition, obesity causes an inflammatory state in the adipose tissue. The recognition that brown/beige adipose tissue is active in adult humans has triggered interest in understanding the physiology and relative importance of these tissues. Exercise and bariatric surgery are known to elicit profound metabolic benefits in type 2 diabetes, although the underlying mechanisms remain unclear. This conference will bring together cell biologists, biochemists, geneticists, physiologists, drug developers and clinical researchers, thereby facilitating knowledge exchange and interactions leading to elucidation of better treatments for obesity and diabetes. Specifically, it will examine recent advances in our understanding of brown/beige adipose tissue function; obesity-induced adipose inflammation; control of adipose tissue, appetite and energy metabolism; endocrine and paracrine signaling via secreted factors; molecular mechanisms of metabolic signaling; emerging topics, including long noncoding RNA and the gut microbiome; and approaches to drug development and the treatment of obesity and diabetes.
View Scholarships/Awards
No registration fees are used to fund entertainment or alcohol at this conference
The meeting will begin on Sunday, February 10 with registration from 16:00 to 20:00 and a welcome mixer from 18:00 to 20:00. Conference events conclude on Thursday, February 14 with a closing plenary session from 17:00 to 19:00, followed by a social hour and entertainment. We recommend return travel on Friday, February 15 in order to fully experience the meeting.
SUNDAY, FEBRUARY 10
MONDAY, FEBRUARY 11
TUESDAY, FEBRUARY 12
WEDNESDAY, FEBRUARY 13
THURSDAY, FEBRUARY 14
FRIDAY, FEBRUARY 15
Conference Program Print | View meeting in 12 hr (am/pm) time
The meeting will begin on Sunday, February 10 with registration from 16:00 to 20:00 and a welcome mixer from 18:00 to 20:00. Conference events conclude on Thursday, February 14 with a closing plenary session from 17:00 to 19:00, followed by a social hour and entertainment. We recommend return travel on Friday, February 15 in order to fully experience the meeting.
SUNDAY, FEBRUARY 10
18:00—20:00
Welcome Mixer
No registration fees are used to fund alcohol served at this function.
08:00—09:00
Welcome and Keynote Address
Meeting has ended...abstracts no longer viewable online.
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Matthias Blüher,
University of Leipzig, Germany
Stanley Ulijaszek,
Institute of Social and Cultural Anthropology, University of Oxford, UK
Framing Obesity as a Problem
Framing Obesity as a Problem
08:00—09:00
Welcome and Keynote Address
Meeting has ended...abstracts no longer viewable online.
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Roger D. Cone,
University of Michigan, USA
Richard D. Palmiter,
HHMI/University of Washington, USA
Neural Circuitry Underlying Feeding Behavior
Neural Circuitry Underlying Feeding Behavior
09:00—11:30
Drug Discovery/Development in Obesity
Meeting has ended...abstracts no longer viewable online.
*
Anne Bouloumié,
INSERM, France
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Philipp E. Scherer,
University of Texas Southwestern Medical Center, USA
Alan R. Saltiel,
University of California, San Diego, USA
Inflammation at the Crossroads of Obesity and Energy Homeostasis
Inflammation at the Crossroads of Obesity and Energy Homeostasis
Coffee Break
Heiko Lickert,
Institute of Diabetes and Regeneration, Germany
Metabolic Impact on Gut Stem Cell Recruitment and Turnover
Metabolic Impact on Gut Stem Cell Recruitment and Turnover
Nana Gletsu-Miller,
Purdue University, USA
Is Bariatric Surgery a Cure for Obesity?
Is Bariatric Surgery a Cure for Obesity?
Sheila Collins,
Vanderbilt University Medical Center, USA
Short Talk: Natriuretic Peptide "Clearance" Receptor NPRC in Adipocytes: Mechanism of Action and Consequences on Lipolysis and Thermogenesis
Short Talk: Natriuretic Peptide "Clearance" Receptor NPRC in Adipocytes: Mechanism of Action and Consequences on Lipolysis and Thermogenesis
Martin Klingenspor,
Technical University of Munich, Germany
Short Talk: A Novel Endocrine Gut–Brown Fat–Brain Axis Controls Satiation
Short Talk: A Novel Endocrine Gut–Brown Fat–Brain Axis Controls Satiation
09:00—11:30
Neural Circuitry Underlying Feeding Behavior
Meeting has ended...abstracts no longer viewable online.
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Gary J. Schwartz,
Albert Einstein College of Medicine, USA
Coffee Break
J. Nicholas Betley,
University of Pennsylvania, USA
Circuits Regulating Nutritive Control of Feeding
Circuits Regulating Nutritive Control of Feeding
Matthew R. Hayes,
University of Pennsylvania, USA
Role of GLP-1 Signaling
Role of GLP-1 Signaling
Jovana Navarrete,
National Institutes of Health, USA
Short Talk: Defined Paraventricular Hypothalamic Populations Exhibit Differential Responses to Food Contingent on Caloric State
Short Talk: Defined Paraventricular Hypothalamic Populations Exhibit Differential Responses to Food Contingent on Caloric State
11:30—12:30
Workshop 1: Research Opportunities in Eating Disorders
Joanna Steinglass,
Columbia University Medical Center/NYSPI, USA
Lara Bethke,
Klarman Family Foundation, USA
Shirly Pinto,
Kallyope, USA
Nathalie Kayadjanian,
Foundation for Prader-Willi Research, USA
15:00—16:30
Workshop 1: Targeting Brown Adipose Tissue for Obesity Treatment
*
Yu-Hua Tseng,
Joslin Diabetes Center/Harvard Medical School, USA
*
Jan Nedergaard,
Stockholm University, Sweden
Katharina Schnabl,
Technical University of Munich, Germany
Screening of Gs-Protein Coupled Receptors in Brown Adipocytes Reveals Adrenocorticotropic Hormone as a Non-Adrenergic Activator of Thermogenesis
Screening of Gs-Protein Coupled Receptors in Brown Adipocytes Reveals Adrenocorticotropic Hormone as a Non-Adrenergic Activator of Thermogenesis
Zach Gerhart-Hines,
University of Copenhagen, Denmark
The Orphan Receptor, GPR3, Activates Thermogenic Fat and Counteracts Obesity Independent of β-Adrenergic Signaling
The Orphan Receptor, GPR3, Activates Thermogenic Fat and Counteracts Obesity Independent of β-Adrenergic Signaling
Alexandra L. Ghaben,
University of Texas Southwestern Medical Center, USA
Insulin Is a Novel Activator of Brown Adipocyte Thermogenesis and Promotes Increased Glucose Substrate Utilization over Lipids
Insulin Is a Novel Activator of Brown Adipocyte Thermogenesis and Promotes Increased Glucose Substrate Utilization over Lipids
Alexandre Caron,
University of Texas Southwestern Medical Center, USA
Journal of Lipid Research Junior Investigator Award: Sympathetic Control of Adipose Endocrine and Metabolic Functions
Journal of Lipid Research Junior Investigator Award: Sympathetic Control of Adipose Endocrine and Metabolic Functions
Ruth Karlina,
Helmholtz Zentrum München, Germany
Defining Murine Brown Adipose Tissue Heterogeneity
Defining Murine Brown Adipose Tissue Heterogeneity
Hyeonwoo Kim,
Dana-Farber Cancer Institute/Harvard Medical School, USA
Irisin Induces Thermogenesis in Fat via Integrin alphaV Receptors
Irisin Induces Thermogenesis in Fat via Integrin alphaV Receptors
17:00—19:00
Brown/Beige/BRITE Fat Activation and Function
Meeting has ended...abstracts no longer viewable online.
*
Barbara Cannon,
Stockholm University, Sweden
*
Steven E. Shoelson,
Harvard Medical School, Joslin Diabetes Center, USA
C. Ronald Kahn,
Joslin Diabetes Center and Harvard Medical School, USA
Adipose Tissue MicroRNAs as Novel Adipokines in Regulation of Metabolism
Adipose Tissue MicroRNAs as Novel Adipokines in Regulation of Metabolism
Camilla Charlotte Schéele,
University of Copenhagen, Denmark
The Plasticity of Human Brown Adipose Tissue
The Plasticity of Human Brown Adipose Tissue
Kirsi A. Virtanen,
Turku University Hospital, University of Turku, Finland
BAT - A Target of Future Weight Loss Strategies
BAT - A Target of Future Weight Loss Strategies
Yu-Hua Tseng,
Joslin Diabetes Center/Harvard Medical School, USA
Short Talk: 12-lipoxygenase Regulates Cold Adaptation and Glucose Metabolism by Producing the Omega-3 Lipid 12-HEPE from Brown Fat
Short Talk: 12-lipoxygenase Regulates Cold Adaptation and Glucose Metabolism by Producing the Omega-3 Lipid 12-HEPE from Brown Fat
Rana K. Gupta,
University of Texas Southwestern Medical Center, USA
Short Talk: Sorting Out Adipocyte Progenitors and their Roles In Adipose Tissue Remodeling
Short Talk: Sorting Out Adipocyte Progenitors and their Roles In Adipose Tissue Remodeling
17:00—19:00
Genetic Disorders of Feeding and Energy Storage
Meeting has ended...abstracts no longer viewable online.
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Herbert Herzog,
Garvan Institute, Australia
Snord116 and its Role in Prader-Willi Syndrome
Snord116 and its Role in Prader-Willi Syndrome
Atul Chopra,
Case Western Reserve University, USA
Human Genetics-Aided Discovery of a New Metabolic Hormone
Human Genetics-Aided Discovery of a New Metabolic Hormone
James Minchin,
University of Edinburgh, UK
Short Talk: Leveraging High-Throughput Mutagenesis and Functional in vivo Imaging in Zebrafish to Identify Genetic Regulators of Human Energy Homeostasis
Short Talk: Leveraging High-Throughput Mutagenesis and Functional in vivo Imaging in Zebrafish to Identify Genetic Regulators of Human Energy Homeostasis
George Stratigopoulos,
Columbia University, USA
Short Talk: Ciliary Gene RPGRIP1L Is Required for POMC Neuron Development and Function
Short Talk: Ciliary Gene RPGRIP1L Is Required for POMC Neuron Development and Function
Lee S. Weinstein,
NIDDK, National Institutes of Health, USA
Short Talk: Mice with MC4R Site Mutation (F51L) Develop Severe Obesity Independent of Gsα/cAMP Signaling
Short Talk: Mice with MC4R Site Mutation (F51L) Develop Severe Obesity Independent of Gsα/cAMP Signaling
19:00—20:00
Social Hour with Lite Bites
No registration fees are used to fund alcohol served at this function.
08:00—11:15
Adipose Tissue and Immune Cells
Meeting has ended...abstracts no longer viewable online.
*
Alan R. Saltiel,
University of California, San Diego, USA
*
Bruce M. Spiegelman,
Harvard Medical School, USA
Anne Bouloumié,
INSERM, France
The Adipose Tissue Immune Cells, Beyond Inflammation
The Adipose Tissue Immune Cells, Beyond Inflammation
Ruth E. Gimeno,
Eli Lilly and Company, USA
New Therapeutic Approaches to Weight Loss and Glucose Control
New Therapeutic Approaches to Weight Loss and Glucose Control
Coffee Break
Tim Julius Schulz,
German Institute of Human Nutrition, Germany
Deciphering the Adipocytic Lineage: Stem Cell Biology and Regeneration
Deciphering the Adipocytic Lineage: Stem Cell Biology and Regeneration
Samuel Klein,
Washington University School of Medicine, USA
Short Talk: Adipose Tissue Immunometabolism
Short Talk: Adipose Tissue Immunometabolism
Shunbun Kita,
Graduate School of Medicine, Osaka University, Japan
Short Talk: Stimulated Exosome Secretion by Adiponectin Contributes to Effectiveness of Mesenchymal Stem Cell Transplantation on Pressure Overload Heart Failure Models
Short Talk: Stimulated Exosome Secretion by Adiponectin Contributes to Effectiveness of Mesenchymal Stem Cell Transplantation on Pressure Overload Heart Failure Models
Stephen E. Flaherty III,
Columbia University, USA
Short Talk: A Lipase-Independent Pathway of Lipid Release and Immune Modulation by Adipocytes via Exosomes
Short Talk: A Lipase-Independent Pathway of Lipid Release and Immune Modulation by Adipocytes via Exosomes
Kathrin Landgraf,
University of Leipzig, Germany
Short Talk: The Obesity Susceptibility Gene TMEM18 Regulates Adipogenesis through Direct Activation of PPARG Signalling in vitro and in vivo
Short Talk: The Obesity Susceptibility Gene TMEM18 Regulates Adipogenesis through Direct Activation of PPARG Signalling in vitro and in vivo
08:00—11:15
Anorexia Nervosa
Meeting has ended...abstracts no longer viewable online.
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Timothy Moran,
Johns Hopkins University School of Medicine, USA
Janet Treasure,
King's College London, UK
Understanding and Treating Anorexia Nervosa
Understanding and Treating Anorexia Nervosa
Walter Kaye,
University of California, San Diego Health, USA
Are Eating Disorders Really Disorders of Eating?
Are Eating Disorders Really Disorders of Eating?
Coffee Break
Jonathan Coleman,
King’s College London, UK
Genome-Wide Association Study of Anorexia Nervosa
Genome-Wide Association Study of Anorexia Nervosa
Lori M. Zeltser,
Columbia University, USA
Identifying Novel Therapeutic Targets for Anorexia Nervosa
Identifying Novel Therapeutic Targets for Anorexia Nervosa
Claire J. Foldi,
Monash University, Australia
Short Talk: The Interplay Between Reward and Control in Anorexia Nervosa: Insights from a Rat Model
Short Talk: The Interplay Between Reward and Control in Anorexia Nervosa: Insights from a Rat Model
Dan J. Christoffel,
Stanford University, USA
Short Talk: Differential Control of Hedonic Feeding by Specific Excitatory Accumbal Inputs
Short Talk: Differential Control of Hedonic Feeding by Specific Excitatory Accumbal Inputs
Qingchun Tong,
University of Texas Medical School, USA
Short Talk: A Lateral Hypothalamus to Basal Forebrain Neurocircuit Promotes Feeding by Suppressing Responses to Anxiogenic Environmental Cues
Short Talk: A Lateral Hypothalamus to Basal Forebrain Neurocircuit Promotes Feeding by Suppressing Responses to Anxiogenic Environmental Cues
15:00—16:30
Workshop 2: White Adipose Tissue Plasticity
*
Iichiro Shimomura,
Osaka University Graduate School of Medicine, Japan
*
Gunnar Mellgren,
University of Bergen, Norway
Sagar P. Bapat,
University of California, San Francisco, USA
Obesity Dysregulates PPAR𝛾 to Drive Th2 Immunopathology
Obesity Dysregulates PPAR𝛾 to Drive Th2 Immunopathology
Clair Crewe,
University of Texas Southwestern Medical Center, USA
Adipocyte Oxidative Stress Induces Mitochondrial-Derived Extracellular Vesicle Production to Regulate Systemic Metabolism
Adipocyte Oxidative Stress Induces Mitochondrial-Derived Extracellular Vesicle Production to Regulate Systemic Metabolism
Siegfried Ussar,
Helmholtz Zentrum Muenchen GmbH, Germany
Asc-1 Regulates White versus Beige Adipocyte Fate in a Stromal Cell Population
Asc-1 Regulates White versus Beige Adipocyte Fate in a Stromal Cell Population
Farnaz Shamsi,
Joslin Diabetes Center, USA
Deconstructing Adipose Tissue Niche Remodeling using Single Cell RNA-Sequencing
Deconstructing Adipose Tissue Niche Remodeling using Single Cell RNA-Sequencing
Keren I. Hilgendorf,
Stanford University, USA
Ω3 Fatty Acids Activate Ffar4/Gpr120 to Trigger Adipogenesis via the Primary Cilium
Ω3 Fatty Acids Activate Ffar4/Gpr120 to Trigger Adipogenesis via the Primary Cilium
17:00—19:00
Adipose Tissue Heterogeneity
Meeting has ended...abstracts no longer viewable online.
*
Francine Côté,
INSERM, France
*
Rana K. Gupta,
University of Texas Southwestern Medical Center, USA
Philipp E. Scherer,
University of Texas Southwestern Medical Center, USA
Mechanisms of Adipose Tissue Dysfunction in Obesity
Mechanisms of Adipose Tissue Dysfunction in Obesity
David B. Savage,
University of Cambridge, UK
A Lipodystrophic Perspective on Insulin Resistance
A Lipodystrophic Perspective on Insulin Resistance
Ellen E. Blaak,
Maastricht University, Netherlands
Sex Differences in Adipose Tissue Metabolism and Tissue-Specific Insulin Resistance
Sex Differences in Adipose Tissue Metabolism and Tissue-Specific Insulin Resistance
Mikael Rydén,
Karolinska Institutet, Sweden
Adipocyte Function and Development in Subcutaneous and Visceral Fat Depots
Adipocyte Function and Development in Subcutaneous and Visceral Fat Depots
17:00—19:00
Neural Circuits Underlying Nausea, Emesis, and Aversive Responses
Meeting has ended...abstracts no longer viewable online.
*
Harvey J. Grill,
University of Pennsylvania, USA
Samuel N. Breit,
St. Vincents Hospital, Australia
The Role of the GDF15-GFRAL in Pathway in Control of Appetite and Energy Homeostasis
The Role of the GDF15-GFRAL in Pathway in Control of Appetite and Energy Homeostasis
Bart C. De Jonghe,
University of Pennsylvania, USA
Neurocircuitry of Nausea in Chemotherapy
Neurocircuitry of Nausea in Chemotherapy
Paul Sabatini,
University of Michigan, USA
Short Talk: Activation of Gfral Neurons Decreases Food Intake
Short Talk: Activation of Gfral Neurons Decreases Food Intake
Qi Wu,
Baylor College of Medicine, USA
Short Talk: Deciphering a Hindbrain Dopaminergic Neural Circuit Mandatory for the Control of Feeding Behavior
Short Talk: Deciphering a Hindbrain Dopaminergic Neural Circuit Mandatory for the Control of Feeding Behavior
19:00—20:00
Social Hour with Lite Bites
No registration fees are used to fund alcohol served at this function.
08:00—11:15
Environment and Obesity
Meeting has ended...abstracts no longer viewable online.
*
Christoph Buettner,
Mount Sinai School of Medicine, USA
*
Kirsi A. Virtanen,
Turku University Hospital, University of Turku, Finland
J. Andrew Pospisilik,
Van Andel Institute, USA
Epigenetic Underpinnings of Metabolic Disease Heterogeneity
Epigenetic Underpinnings of Metabolic Disease Heterogeneity
Nathalie Delzenne,
Université Catholique de Louvain, Belgium
Dealing with the Gut Microbiota in Obesity
Dealing with the Gut Microbiota in Obesity
Coffee Break
Bruce A. Bunnell,
Tulane University School of Medicine, USA
The Impact of Endocrine Disrupting Chemicals on the Biology of Mesenchyaml Stem Cells
The Impact of Endocrine Disrupting Chemicals on the Biology of Mesenchyaml Stem Cells
Kristen E. Boyle,
University of Colorado School of Medicine, USA
Maternal Obesity and Offspring Adiposity: Clues from Umbilical Cord Mesenchymal Stem Cells
Maternal Obesity and Offspring Adiposity: Clues from Umbilical Cord Mesenchymal Stem Cells
Ashley A. Able,
Louisiana State University, USA
Short Talk: Inhibition of H3K9 Methyltransferase, GLP, Promotes Metabolically Healthy Gene Expression in Adipocytes
Short Talk: Inhibition of H3K9 Methyltransferase, GLP, Promotes Metabolically Healthy Gene Expression in Adipocytes
David Merrick,
University of Pennsylvania, USA
Short Talk: Identification of a Mesenchymal Progenitor Cell Hierarchy in Adipose Tissue
Short Talk: Identification of a Mesenchymal Progenitor Cell Hierarchy in Adipose Tissue
08:00—11:00
Telencephalic Control of Feeding Behavior
Meeting has ended...abstracts no longer viewable online.
*
Jonathan Dean Hommel,
University of Texas Medical Branch, USA
Benjamin R. Arenkiel,
Baylor College of Medicine, USA
Excitatory Basal Forebrain Circuits Promote Food Avoidance
Excitatory Basal Forebrain Circuits Promote Food Avoidance
Coffee Break
Mark L. Andermann,
Beth Israel Deaconess Medical Center, USA
State-Specific Gating of Motivationally Salient Cues by Midbrain Dopaminergic Inputs to Basal Amygdala
State-Specific Gating of Motivationally Salient Cues by Midbrain Dopaminergic Inputs to Basal Amygdala
Ivan E. de Araujo,
Icahn School of Medicine at Mount Sinai, USA
Vagal Control of Brain Reward Systems
Vagal Control of Brain Reward Systems
Sarah Stern,
Rockefeller University, USA
Short Talk: A Molecularly Defined Insular Cortex to Central Amygdala Circuit Controls Cue-Mediated Overconsumption
Short Talk: A Molecularly Defined Insular Cortex to Central Amygdala Circuit Controls Cue-Mediated Overconsumption
Christopher D. Morrison,
Pennington Biomedical Research Center, USA
Short Talk: FGF21 Signals Protein Status to the Brain and Adaptively Regulates Food Choice and Metabolism
Short Talk: FGF21 Signals Protein Status to the Brain and Adaptively Regulates Food Choice and Metabolism
15:00—16:30
Workshop 3: Adipose Tissue Heterogeneity
*
Patrick Seale,
University of Pennsylvania, USA
*
Silvia Corvera,
University of Massachusetts Medical School, USA
Yu An,
University of Texas Southwestern Medical Center, USA
Mitochondrial Dicarboxylate Carrier (SLC25A10), a Regulator of Adipocyte Mitochondrial Function and Obesity
Mitochondrial Dicarboxylate Carrier (SLC25A10), a Regulator of Adipocyte Mitochondrial Function and Obesity
Vicky Wang-wei Tsai,
St Vincent’s Hospital and University of New South Wales, Australia
Treatment with GDF15 Reduces the Adiposity and Corrects the Metabolic Dysfunction of Mice with Diet-Induced Obesity
Treatment with GDF15 Reduces the Adiposity and Corrects the Metabolic Dysfunction of Mice with Diet-Induced Obesity
Andrea Galmozzi,
The Scripps Research Institute, USA
PGRMC2 Is an Intracellular Heme Chaperone Critical for Adipocyte Function
PGRMC2 Is an Intracellular Heme Chaperone Critical for Adipocyte Function
Olivier Bezy,
Pfizer Inc., USA
Contrasting Effects of Acute Versus Chronic Treatment with Urocortin 2 on Diet-Induced Obesity and Insulin Resistance
Contrasting Effects of Acute Versus Chronic Treatment with Urocortin 2 on Diet-Induced Obesity and Insulin Resistance
Rebecca Wafer,
University of Edinburgh, UK
In vivo Imaging in Zebrafish Identifies Novel Genetic Regulators of Subcutaneous Fat Levels
In vivo Imaging in Zebrafish Identifies Novel Genetic Regulators of Subcutaneous Fat Levels
Nathalie Boulet,
INSERM, France
The Heterogeneity in Progenitor Cell Subsets Contributes to the Intrinsic Remodeling Capacity of Human Fat Depots
The Heterogeneity in Progenitor Cell Subsets Contributes to the Intrinsic Remodeling Capacity of Human Fat Depots
17:00—19:00
How Can We Translate Novel Discoveries into Obesity Treatment?
Meeting has ended...abstracts no longer viewable online.
*
Ruth E. Gimeno,
Eli Lilly and Company, USA
*
C. Ronald Kahn,
Joslin Diabetes Center and Harvard Medical School, USA
Kevin L. Grove,
Novo Nordisk, USA
Anti-Obesity Drug Development: The Potential and the Challenges
Anti-Obesity Drug Development: The Potential and the Challenges
Barbara B. Kahn,
Beth Israel Deaconess Medical Center, Harvard Medical School, USA
Adipose Tissue-Derived Lipokines
Adipose Tissue-Derived Lipokines
Max Nieuwdorp,
University of Amsterdam, Netherlands
The Gut Microbiome – Tool or Target for Obesity Treatment?
The Gut Microbiome – Tool or Target for Obesity Treatment?
Gerson S. Profeta,
University of Campinas, Brazil
Short Talk: Fluoroquinolone-Related Molecules: Promising Drugs to Increase Browning of White Fat and miRNA Biogenesis
Short Talk: Fluoroquinolone-Related Molecules: Promising Drugs to Increase Browning of White Fat and miRNA Biogenesis
Xiaoyong Yang,
Yale University School of Medicine, USA
Short Talk: Adipocyte OGT Governs Diet-Induced Hyperphagia and Obesity
Short Talk: Adipocyte OGT Governs Diet-Induced Hyperphagia and Obesity
17:00—19:00
Feeding Across the Lifespan
Meeting has ended...abstracts no longer viewable online.
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Shane T. Hentges,
Colorado State University, USA
Sebastien G. Bouret,
University of Southern California, USA
Molecular Mechanisms Controlling Development of Hypothalamic Feeding Circuits
Molecular Mechanisms Controlling Development of Hypothalamic Feeding Circuits
Kelly L. Klump,
Michigan State University, USA
Developmental Differences in Neurobiological Risk Factors for Binge Eating across Adolescence: Evidence from Animal and Human Models
Developmental Differences in Neurobiological Risk Factors for Binge Eating across Adolescence: Evidence from Animal and Human Models
Patricia O. Prada,
University of Campinas, Brazil
Short Talk: Maternal Exposure to Air Pollution during Lactation Induces Hyperphagia, Obesity and Altered Glucose Homeostasis in a Gender-Specific Fashion in Adult Offspring
Short Talk: Maternal Exposure to Air Pollution during Lactation Induces Hyperphagia, Obesity and Altered Glucose Homeostasis in a Gender-Specific Fashion in Adult Offspring
Alexandre Fisette,
Helmholtz Zentrum München, Germany
Short Talk: Functional Identity of Hypothalamic Melanocortin Neurons Depends on Tbx3
Short Talk: Functional Identity of Hypothalamic Melanocortin Neurons Depends on Tbx3
19:00—20:00
Social Hour with Lite Bites
No registration fees are used to fund alcohol served at this function.
08:00—11:00
Disease Cachexia (Joint)
Meeting has ended...abstracts no longer viewable online.
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Clifford J. Rosen,
Maine Medical Center, USA
Stefan D. Anker,
Universitätsmedizin Berlin, Germany
Cardiac Cachexia
Cardiac Cachexia
Bruce M. Spiegelman,
Harvard Medical School, USA
Regulation of Mitochondria and Oxidative Metabolism: Futile Creatine Cycle (FCC)
Regulation of Mitochondria and Oxidative Metabolism: Futile Creatine Cycle (FCC)
Coffee Break
Daniel L. Marks,
Oregon Health & Science University, USA
Neural Circuitry Mediating Cachexia
Neural Circuitry Mediating Cachexia
Roger D. Cone,
University of Michigan, USA
The Melanocortin-3 Receptor as a Drug Target for Cachexia and Anorexia
The Melanocortin-3 Receptor as a Drug Target for Cachexia and Anorexia
15:00—16:30
Clinical Obesity Management – Round Table Discussion
*
Timo D. Müller,
Institute for Diabetes and Obesity, Germany
Matthias Blüher,
University of Leipzig, Germany
Samuel Klein,
Washington University School of Medicine, USA
14:30—16:30
Workshop 2: Late Breaking Topics from Abstracts
*
Michael Krashes,
NIDDK, National Institutes of Health, USA
Wei Xie,
Harrington Discovery Institute, USA
Identification of an Asprosin Receptor
Identification of an Asprosin Receptor
Anda Cornea,
Novo Nordisk Research Center, USA
Distribution of Fluorescently Labeled Leptin in the Brain of Lean and DIO Mice
Distribution of Fluorescently Labeled Leptin in the Brain of Lean and DIO Mice
Isin Cakir,
University of Michigan, USA
Inhibition of Histone Deacetylase 6 (HDAC6) Reverses Diet-Induced Obesity
Inhibition of Histone Deacetylase 6 (HDAC6) Reverses Diet-Induced Obesity
Olivia D. Osborn,
University of California, San Diego, USA
A Novel Approach to Block Antipsychotic-Induced Food Intake and Weight Gain
A Novel Approach to Block Antipsychotic-Induced Food Intake and Weight Gain
Maria Caterina De Rosa,
Columbia University, USA
Generation of Paraventricular Hypothalamic Neurons from Human Pluripotent Stem Cells
Generation of Paraventricular Hypothalamic Neurons from Human Pluripotent Stem Cells
Tim Gruber,
Helmholtz Center Munich, Germany
Remodeling of the Hypothalamic Vasculature upon Hypercaloric Feeding Depends on Astroglial HIF1α and VEGF
Remodeling of the Hypothalamic Vasculature upon Hypercaloric Feeding Depends on Astroglial HIF1α and VEGF
Sinisa Hrvatin,
Harvard Medical School, USA
PESCA: A Scalable Platform for the Development of Cell-Type-Specific Viral Drivers
PESCA: A Scalable Platform for the Development of Cell-Type-Specific Viral Drivers
Chrissa Dwyer,
Ionis Pharmaceuticals, USA
Distribution and Activity of Antisense Oligonucleotides in the CNS of Rodents and Primates following Central Administration
Distribution and Activity of Antisense Oligonucleotides in the CNS of Rodents and Primates following Central Administration
17:00—18:45
Adipose Tissue Microenvironment
Meeting has ended...abstracts no longer viewable online.
*
Kevin L. Grove,
Novo Nordisk, USA
Christoph Buettner,
Mount Sinai School of Medicine, USA
Adipose Tissue Adaptive Thermogenesis
Adipose Tissue Adaptive Thermogenesis
Catherine C. Muller-Staumont,
IPBS CNRS UMR 5089, France
Adipose Tissue and Cancer: A Dangerous Dynamic Duo
Adipose Tissue and Cancer: A Dangerous Dynamic Duo
Steven E. Shoelson,
Harvard Medical School, Joslin Diabetes Center, USA
Adipose Tissue Microenvironment as Target of New Emerging Therapies
Adipose Tissue Microenvironment as Target of New Emerging Therapies
Silvia Corvera,
University of Massachusetts Medical School, USA
Short Talk: Mechanisms of Development of Human Adipocyte Heterogeneity
Short Talk: Mechanisms of Development of Human Adipocyte Heterogeneity
17:00—18:45
Drug Discovery for Eating Disorders
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Ruth E. Gimeno,
Eli Lilly and Company, USA
Peter Kuehnen,
Charité – Universitätsmedizin Berlin, Germany
Treatment of Monogenic Eating Disorders
Treatment of Monogenic Eating Disorders
Shamina M. Rangwala,
Janssen, Johnson & Johnson, USA
Novel Therapeutics for Eating Disorders – Targeting the GDF15/GFRAL Axis and Beyond
Novel Therapeutics for Eating Disorders – Targeting the GDF15/GFRAL Axis and Beyond
Xinle Wu,
Eli Lilly and Company, China
The Metabolic Effects of GDF15 Are Mediated by the Orphan Receptor GFRAL
The Metabolic Effects of GDF15 Are Mediated by the Orphan Receptor GFRAL
Robert Haws,
Marshfield Medical Research Foundation, USA
Short Talk: Clinical Study Experience of the MC4R Agonist Setmelanotide in the Treatment of Rare Genetic Disorders of Obesity: Results from Bardet Biedl Syndrome and Alström Syndrome Cohorts in a Phase 2 Open Label Study
Short Talk: Clinical Study Experience of the MC4R Agonist Setmelanotide in the Treatment of Rare Genetic Disorders of Obesity: Results from Bardet Biedl Syndrome and Alström Syndrome Cohorts in a Phase 2 Open Label Study
18:45—19:00
Meeting Wrap-Up: Outcomes and Future Directions (Organizers)
Meeting has ended...abstracts no longer viewable online.
18:45—19:00
Meeting Wrap-Up: Outcomes and Future Directions (Organizers)
Meeting has ended...abstracts no longer viewable online.
19:00—20:00
Social Hour with Lite Bites
No registration fees are used to fund alcohol served at this function.
20:00—23:00
Entertainment
Entertainment is not subsidized by conference registration fees nor any U.S. federal government grants. Funding for this expense is provided by other revenue sources.
*Session Chair †Invited, not yet responded.
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