Keystone Resort Floorplan

Registered Attendees


Registered attendees (and speakers, organizers, etc.) will have access to the following items from their Account page:

  • Abstracts from speakers and poster sessions, including the joint meeting abstracts, available 30 days prior to the meeting (You can edit your own abstract from My Account page as well)

    NOTE: Abstract authors/submitters may choose to not have their abstract available online and in the secure mobile app until a week before the meeting.

  • Full participant list, including joint meeting participants
  • Printable Invoices and Invitation Letters
  • Scholarship Information
  • Lodging Information

Login to My Account page

Cellular Plasticity: Reprogramming, Regeneration and Metaplasia (J3)

joint with the meeting on Signal Dynamics and Signal Integration in Development and Disease (J4)

Scientific Organizers: Jason C. Mills, Maike Sander and Ben Z. Stanger


January 27—31, 2019

Keystone Resort, Keystone, Colorado, USA


Sponsored by Novartis Institutes for BioMedical Research and 10x Genomics


IT’S NOT TOO LATE TO SUBMIT YOUR ABSTRACT. Abstracts received can no longer be considered for oral short talks. Abstracts for poster display opportunities will be accepted until 6 weeks before meeting start date midnight MST.
BEWARE of booking lodging through companies unaffiliated with Keystone Symposia. Click here for more details.

Keystone Symposia is committed to maintaining a positive and respectful environment at its meetings. To this end, please review and comply with our policies.

Registered attendees of one meeting in a joint pair may participate in sessions of the other, pending space availability.

DEADLINES:
*All deadlines end at 11:59 PM US Mountain Standard Time
Scholarship Deadline: Oct 17, 2018 [details]
Discounted Abstract Deadline: Oct 17, 2018 [details]
Abstract Deadline: Oct 25, 2018 [details]
Discounted Registration Deadline: Nov 28, 2018 [details]

Click here to view Cancellation Policy

Submit an Abstract Register Yourself Deadlines and Fees

Rates and Deadlines listed below are for the 2019-J3 "Cellular Plasticity: Reprogramming, Regeneration and Metaplasia" conference only.

*All deadlines end at 11:59 PM US Mountain Standard Time

Deadline Date Cost
Discounted Abstract Deadline
More details
Before and On October 17, 2018 100.00 USD*
- 50.00 USD discount
Abstract Deadline
More details
After October 17, 2018 until December 16, 2018 100.00 USD*
* 50.00 USD of Abstract fee deducted from your registration fee when you register for this meeting
Scholarship
More details
October 17, 2018 n/a
Discounted NON-STUDENT Registration
More details
Before and On November 28, 2018 845.00 USD
(includes 200.00 discount)
Regular NON-STUDENT Registration
More details
After November 28, 2018 1045.00 USD
Discounted STUDENT Registration
More details
Before and On November 28, 2018 620.00 USD
(includes 200.00 discount)
Regular STUDENT Registration
More details
After November 28, 2018 820.00 USD

* Changes in payment type that result in a refund are subject to a processing fee.
* Currency exchange gains/losses are the responsibility of the registrant and the Keystone Symposia will accept no liability for money loss through bank charges, transfers or currency fluctuations.




Discounted Abstract Deadline: October 17, 2018

*All deadlines end at 11:59 PM US Mountain Standard Time

Abstract Submission Fee: 100.00 USD*
Submission by this date receives 50.00 USD discount.
*50.00 USD will be applied to Registration Fee when you register

Abstract Details: It is best to submit your abstract early. Abstract and registration spaces are limited and may fill prior to the abstract or discounted registration deadlines. Submitting an abstract does not constitute or guarantee registration.

Submitting your abstract early allows us to:
  • submit your abstract to organizers to be considered for a short talk
  • accept your abstract online
  • include your abstract on our website and in our secure mobile app
  • reserve your space at the meeting for a poster presentation.**
**Submitting an abstract does not constitute or guarantee registration.
(The Abstract Deadline: is October 25, 2018)

Global Health Travel Award Deadline:

*All deadlines end at 11:59 PM US Mountain Standard Time


Global Health Travel Award Details: You MUST complete your Global Health Travel Award appplication by the Global Health Travel Award Deadline and complete the other required steps (verify your contact information and submit a recommendation letter) to be considered for a travel award.


Click here to learn more about Global Health Travel Awards.

Scholarship Deadline: October 17, 2018

*All deadlines end at 11:59 PM US Mountain Standard Time


Scholarship Details: You MUST submit your abstract by the Scholarship Deadline and complete the other required steps (submit a scholarship application and submit a mentor letter) to be considered for a scholarship.

Click here to learn more about Scholarships.

Abstract Deadline: October 25, 2018

*All deadlines end at 11:59 PM US Mountain Standard Time


Abstract Submission Fee: 100.00 USD*
*50.00 USD will be applied to Registration Fee when you register

Details: It is best to submit your abstract early. Abstract and registration spaces are limited and may fill prior to the abstract or discounted registration deadline. Submitting an abstract does not constitute or guarantee registration.

Submitting your abstract by the Abstract Deadline allows us to:

  • submit your abstract to organizers to be considered for a short talk
  • include your abstract on our website and in our secure mobile app
  • reserve your space at the meeting for a poster presentation.**
**Submitting an abstract does not constitute or guarantee registration.
Abstracts submitted after the Abstract Deadline will NOT be considered for a short talk.

(Discounted Abstract Deadline: is October 17, 2018)

Discounted Registration Deadline: November 28, 2018

*All deadlines end at 11:59 PM US Mountain Standard Time


Registration Fee: 845.00 USD* (includes 200.00 USD discount)
Student Registration Fee: 620.00 USD* (must complete student verification form)

*Includes 50.00 USD of your abstract submission fee

After the Discounted Registration Deadline:


Registration Fee: 1045.00 USD*
Student Registration Fee: 820.00 USD* (must complete student verification form)

*Includes 50.00 USD of your abstract submission fee

Registration spaces are limited and may fill prior to discounted registration deadline.

Please be advised that some meeting participants have received calls and emails from a number of different housing services, including "Exhibitors Housing Services," “Expo Housing Services,” "Global Housing," etc. THESE COMPANIES ARE NOT AFFILIATED WITH KEYSTONE SYMPOSIA and are not authorized by Keystone Symposia to contact you. These companies may tell you that the meeting is filling, without any actual knowledge to that effect, and pressure you into giving them your credit card number to make a lodging reservation with them.

We highly recommend that you not make a reservation with these companies or any other housing service! These companies' representations to participants have been misleading. Please report any calls or correspondence you might have received to Keystone Symposia and book only through lodging links in your Keystone Symposia account, an established travel agency or directly with the hotel(s) listed on our website.
No registration fees are used to fund entertainment or alcohol at this conference

Conference Program    Print  |   View meeting in 12 hr (am/pm) time


The meeting will begin on Sunday, January 27 with registration from 16:00 to 20:00 and a welcome mixer from 18:00 to 20:00. Conference events conclude on Thursday, January 31 with a closing plenary session from 17:00 to 19:00, followed by a social hour and entertainment. We recommend return travel on Friday, February 1 in order to fully experience the meeting.

SUNDAY, JANUARY 27

16:00—20:00
Arrival and Registration

Longs Peak Foyer
18:00—20:00
Welcome Mixer
No registration fees are used to fund alcohol served at this function.

Longs Peak Foyer

MONDAY, JANUARY 28

07:00—08:00
Breakfast

Colorado Rockies Ballroom
08:00—09:00
Welcome and Keynote Address (Joint)
Registered attendees can view abstracts starting on 12/27/2018

Columbine Ballroom
Hans C. Clevers, Hubrecht Institute, Netherlands
Lgr5 Stem Cell-Based Organoids in Human Disease

09:00—11:15
Plasticity and Signaling in Development and Homeostasis (Joint)
Registered attendees can view abstracts starting on 12/27/2018

Columbine Ballroom
Jayaraj Rajagopal, Massachusetts General Hospital, USA
The Airway Epithelial Ensemble

Coffee Break

Ophir Klein, University of California, San Francisco, USA
Talk Title to be Announced

Valentina Greco, Yale School of Medicine, USA
Signaling and Cell Competition in Skin

Erin N. Sanders, Stanford University, USA
Short Talk: Real-Time Kinetics of Notch-Mediated Fate Decisions during Organ Renewal

Richard (Shiyan) Yu, Rutgers University-Newark, USA
Short Talk: Injury Induces Paneth Cell Plasticity

11:15—17:00
On Own for Lunch

11:15—13:00
Poster Setup

Colorado Rockies Ballroom
13:00—22:00
Poster Viewing

Colorado Rockies Ballroom
14:30—16:30
Workshop

Grays/Longs Peak
Julie B. Sneddon, University California, San Francisco, USA
Cell Fate Determination in Human Pancreatic Endocrine Development

P. Duc Si Dong, Sanford Burnham Prebys Medical Discovery Institute, USA
Biliary Paucity Due Jagged/Notch Loss is Reversible via a Novel Non-Hepatic Multipotent Cell Population

Micha Sam Brickman Raredon, Yale University, USA
Cross-Species scRNAseq Analysis of Cell-Cell Connectomics in Lung

Jarod Zepp, University of Pennsylvania, USA
Epithelial to Mesenchymal Crosstalk during the Postnatal Phase of Lung Development Coordinates Lineage Commitment and Niche Formation

Oliver Wessely, Cleveland Clinic Foundation, USA
A Design-of-Experiment Approach Towards Differentiation of Human Pluripotent Stem Cells into Definitive Kidney Cell Lineages

Li-Fang Chu, University of Wisconsin-Madison, USA
Comparative, High Temporal Resolution Transcriptomic Analysis of Human and Mouse Embryonic Stem Cells Differentiation Towards Definitive Endoderm Reveals Conserved and Unique Coding and Non-Coding Gene Expression Repertoire

Akiko Mammoto, Medical College of Wisconsin, USA
Effects of Age-Dependent Changes in Cell Size on Endothelial Cell Growth through YAP1

16:30—17:00
Coffee Available

Longs Peak Foyer
17:00—19:00
Stem Cell Recruitment and Metaplasia
Registered attendees can view abstracts starting on 12/27/2018

Quandary Peak
Calvin Kuo, Stanford University, USA
Intestinal Stem Cell Niches

Jason C. Mills, Washington University, USA
Reserve Stem Cells Recruited by Paligenosis, an Evolutionarily Conserved Program

Anil K. Rustgi, University of Pennsylvania, USA
Metaplasia in Esophagus and Pancreas

Short Talk(s) Chosen from Abstracts

17:00—19:00
Quantitative Approaches and Signaling Networks
Registered attendees can view abstracts starting on 12/27/2018

Grays/Longs Peak
Michael Elowitz, California Institute of Technology, USA
Communication and Computation in Protein Circuits

Ertugrul M. Ozbudak, Cincinnati Children's Hospital Medical Center, USA
Spatial Fold-Change of FGF Signaling Encodes Positional Information for Segmental Determination in Zebrafish

Mary N. Teruel, Stanford University, USA
A Transcriptional Circuit Filters Oscillating Circadian Hormonal Inputs to Regulate Fat Cell Differentiation

Jared Toettcher, Princeton University, USA
Short Talk: Cellular Optogenetics Reveals Principles of Cell Fate Control in the Early Drosophila Embryo

Amanda L. Zacharias, Cincinnati Children's Hospital Medical Center, USA
Short Talk: Comprehensive Quantitative Analysis of Nuclear β-catenin in C. elegans Embryos Identifies a Novel Memory Mechanism for Gene Expression Diversification

19:00—20:00
Social Hour with Lite Bites
No registration fees are used to fund alcohol served at this function.

Colorado Rockies Ballroom
19:30—22:00
Poster Session 1

Colorado Rockies Ballroom

TUESDAY, JANUARY 29

07:00—08:00
Breakfast

Colorado Rockies Ballroom
08:00—11:00
Cancer and Plasticity
Registered attendees can view abstracts starting on 12/27/2018

Quandary Peak
Arjun Raj, University of Pennsylvania, USA
Controlling Cellular Plasticity in Cancer

Ben Z. Stanger, University of Pennsylvania, USA
Epithelial-mesenchymal Plasticity in Cancer Cell Invasion and Metastasis

Coffee Break

Carla F. Kim, Boston Children's Hospital, USA
Regulation of Progenitor Cells in the Adult Lung

Cory T. Abate-Shen, Columbia University Medical Center, USA
Cellular Plasticity in Prostate Cancer

Short Talk(s) Chosen from Abstracts

08:00—11:00
Signaling Dynamics
Registered attendees can view abstracts starting on 12/27/2018

Grays/Longs Peak
Vivian Li, Francis Crick Institute, UK
Wnt Signal Regulation in Intestinal Stem Cell and Cancer

Deborah L. Gumucio, University of Michigan, USA
Dynamic Roles for WNT5a During Morphogenesis of the Mouse Fetal Intestine

Coffee Break

Raphael Kopan, University of Cincinnati College of Medicine, USA
Notch Signaling in Renal Development and Renal Stem Cells

Victoria Ng, Vanderbilt University, USA
Short Talk: The USP46 Complex Promotes Wnt Signaling by Blocking Receptor Turnover

Sergi Regot, Johns Hopkins University, USA
Short Talk: Single Cell Analysis of MAPK Signaling Dynamics in Multicellular Systems

David Sprinzak, Tel Aviv University, Israel
Short Talk: Localized Feedbacks on Fat4-Ds1 Complexes Underlie Planar Cell Polarity

Kaelyn Sumigray, Duke University, USA
Short Talk: Morphogenesis and Compartmentalization of the Mammalian Intestine

11:00—17:00
On Own for Lunch

11:00—13:00
Poster Setup

Colorado Rockies Ballroom
13:00—22:00
Poster Viewing

Colorado Rockies Ballroom
16:30—17:00
Coffee Available

Longs Peak Foyer
17:00—19:00
Reprogramming Cells to Assemble and Repair Organs
Registered attendees can view abstracts starting on 12/27/2018

Quandary Peak
Jason R. Spence, University of Michigan Health System, USA
Intestinal Organoids

Takanori Takebe, Yokohama City University / Cincinnati Children's Hospital Medical Center, Japan
Next-Gen Organoids from Pluripotency

Meritxell Huch, University of Cambridge, UK
Hepatic Organoids for the Understanding of Liver Regeneration and Disease

Short Talk(s) Chosen from Abstracts

17:00—19:00
Morphogen Gradients in Growth and Patterning
Registered attendees can view abstracts starting on 12/27/2018

Grays/Longs Peak
Caroline S. Hill, Francis Crick Institute, UK
Self-Organising Pattern Formation in Endoderm Specification in Zebrafish

Anna Kicheva, Institute of Science and Technology Austria, Austria
Coordination of Progenitor Specification and Growth in the Developing Spinal Cord

J. P. Vincent, Francis Crick Institute, UK
Coordination of Growth and Patterning in a Developing Epithelium

Jennifer Kong, Stanford University, USA
Short Talk: Molecular Mechanisms that Regulate Target Cell Sensitivity to Hedgehog Morphogens

Shinji Takada, National Institute for Basic Biology, Japan
Short Talk: Extracellular Dynamics and Diffusion Range of Wnt Protein Complex in Xenopus Embryos

19:00—20:00
Social Hour with Lite Bites
No registration fees are used to fund alcohol served at this function.

Colorado Rockies Ballroom
19:30—22:00
Poster Session 2

Colorado Rockies Ballroom

WEDNESDAY, JANUARY 30

07:00—08:00
Breakfast

Colorado Rockies Ballroom
08:00—11:00
Plasticity and Signaling in Regeneration and Tumorigenesis (Joint)
Registered attendees can view abstracts starting on 12/27/2018

Columbine Ballroom
Jeffrey L. Wrana, Mount Sinai Hospital, Canada
TGFbeta and Hippo in Cancer and Regeneration

Maike Sander, University of California, San Diego, USA
Epigenetic Regulation of Developmental Competence

Coffee Break

Stacey S. Huppert, Cincinnati Children’s Hospital Medical Center, USA
Building a Functional Biliary System from Hepatocytes

Owen J. Sansom, Beatson Institute of Cancer Research, UK
Reserve Stem Cells and Intestinal Tumorigenesis

Margaret E. Magaletta, University of Massachusetts Medical School, USA
Short Talk: Single Cell Transcriptomic Analysis Resolves Dynamics of Developing Pharyngeal Endoderm

Won Jae Huh, , USA
Short Talk: Transforming Growth Factor-α (TGFα) Overexpression Induces Spasmolytic Polypeptide Expressing Metaplasia (SPEM) in the Stomach via EGF Receptor (EGFR) Signaling in Chief Cells

11:00—17:00
On Own for Lunch

11:00—13:00
Poster Setup

Colorado Rockies Ballroom
13:00—22:00
Poster Viewing

Colorado Rockies Ballroom
14:30—16:30
Workshop: Nomenclature in Cell Plasticity: 'Plasticity', 'Dedifferentiation', 'Transdifferentiation', 'Reprogramming', 'Reversion' – Can We Agree What These Mean?

Quandary Peak
Short Talks Chosen from Abstracts

16:30—17:00
Coffee Available

Longs Peak Foyer
17:00—19:00
Transcriptional Regulation of Cell Plasticity
Registered attendees can view abstracts starting on 12/27/2018

Quandary Peak
Ramesh A. Shivdasani, Dana-Farber Cancer Institute, USA
Epigenetic Regulation of Gut Development and Plasticity

Scott T. Magness, University of North Carolina at Chapel Hill, USA
Sox9 Regulates Reserve Intestinal Stem Cell Function

Michele A. Battle, Medical College of Wisconsin, USA
Transcriptional Regulation of Barrett’s Metaplasia

Short Talk(s) Chosen from Abstracts

17:00—19:00
Cell Competition and Mechanical Interactions
Registered attendees can view abstracts starting on 12/27/2018

Grays/Longs Peak
Eugenia Piddini, University of Bristol, UK
Mechanical Competition in Mammals and Flies

Miguel Torres, Centro Nacional de Investigaciones Cardiovasculares, Spain
Cell Competition in Mammalian Development and Tissue Homeostasis

Nicolas Tapon, Francis Crick Institute, UK
Growth Control and Hippo Signaling in the Drosophila Abdomen

Giulia Pilia, Uppsala Universitet, Sweden
Short Talk: Ack1 is a Mechanoresponsive Kinase Required for Regulation of Yap/Taz

Anne-Marie Pret, University of Versailles St Quentin-en-Yvelines, France
Short Talk: JAK/STAT Signaling and Epithelial Homeostasis in Drosophila

19:00—20:00
Social Hour with Lite Bites
No registration fees are used to fund alcohol served at this function.

Colorado Rockies Ballroom
19:30—22:00
Poster Session 3

Colorado Rockies Ballroom

THURSDAY, JANUARY 31

07:00—08:00
Breakfast

Colorado Rockies Ballroom
08:00—11:00
Injury, Inflammation and Regeneration
Registered attendees can view abstracts starting on 12/27/2018

Quandary Peak
Irene Miguel-Aliaga, Imperial College London, UK
Sex, Reproduction and Intestinal Plasticity

Xin Sun, University of California, San Diego, USA
Neural-Immune Niches in the Airway

Coffee Break

Juanita L. Merchant, University of Arizona College of Medicine, USA
How Do Immune Cells Reprogram the Epithelium?

James R. Goldenring, Vanderbilt University Medical Center, USA
Inflammatory Regulation of Metaplasia Induction in the Stomach

Short Talk(s) Chosen from Abstracts

08:00—11:00
Developmental Signaling and Disease
Registered attendees can view abstracts starting on 12/27/2018

Grays/Longs Peak
Adolfo Ferrando, Columbia University, USA
Notch in T-Cell Acute Lymphoblastic Leukemia

Feng Cong, Novartis Institutes for BioMedical Research, USA
Drug Discovery for the Wnt, TGFß/BMP, and HIPPO Pathways

Coffee Break

Kun-Liang Guan, University of California, San Diego, USA
Hippo Signaling in Cancer

Aris N. Economides, Regeneron Pharmaceuticals, Inc., USA
Activin Ligand Traps in Bone Disease Treatment

Zlatko Trajanoski, Medical University of Innsbruck, Austria
Short Talk: Perturbation Biology of Colorectal Cancer Organoids Reveals Patient-Specific Signaling Rewiring and Interference with Immunity

Dominique Celeste Mitchell, University of California San Francisco, USA
Short Talk: Small Molecule Activation of LKB1 Reveals Multiphasic Hippo Pathway Signal Buffering

11:00—17:00
On Own for Lunch

16:30—17:00
Coffee Available

Longs Peak Foyer
17:00—18:45
Applications of Cell Plasticity
Registered attendees can view abstracts starting on 12/27/2018

Quandary Peak
Frederic J. de Sauvage, Genentech, Inc., USA
Targeting Intestinal Stem Cells in Cancer

Joe Q. Zhou, Harvard Stem Cell Institute, USA
Making Insulin-Secreting Cells from Intestine

Darrell N. Kotton, Boston University, USA
Pluripotent Stem Cell Models of Lung Development and Disease

Short Talk Chosen from Abstracts

17:00—18:45
Integration of Developmental Signaling Pathways
Registered attendees can view abstracts starting on 12/27/2018

Grays/Longs Peak
Liliana Attisano, University of Toronto, Canada
Hippo in Cancer

Norbert Perrimon, Harvard Medical School, USA
Insights on the Role of Ion Channels in the Drosophila Gut Epithelium

Lukasz Bugaj, University of Pennsylvania, USA
High-Throughput Multicolor Optogenetics for the Systematic Dissection of Signal Dynamics and Integration

Andrei V. Karginov, University of Illinois at Chicago, USA
Short Talk: Interrogation of Signaling Pathways using Light-Regulated Protein Kinases

18:45—19:00
Meeting Wrap-Up: Outcomes and Future Directions (Organizers)
Registered attendees can view abstracts starting on 12/27/2018

Quandary Peak
18:45—19:00
Meeting Wrap-Up: Outcomes and Future Directions (Organizers)
Registered attendees can view abstracts starting on 12/27/2018

Grays/Longs Peak
19:00—20:00
Social Hour with Lite Bites
No registration fees are used to fund alcohol served at this function.

Colorado Rockies Ballroom
20:00—23:00
Entertainment
Entertainment is not subsidized by conference registration fees nor any U.S. federal government grants. Funding for this expense is provided by other revenue sources.

Colorado Rockies Ballroom

FRIDAY, FEBRUARY 1

 
Departure


*Session Chair †Invited, not yet responded.



We gratefully acknowledge support for this conference from:


Directors' Fund


These generous unrestricted gifts allow our Directors to schedule meetings in a wide variety of important areas, many of which are in the early stages of research.

Click here to view all of the donors who support the Directors' Fund.



Keystone Symposia thanks our Sponsor for generously supporting this meeting:

Novartis Institutes for BioMedical Research

We gratefully acknowledge additional support from these exhibitors at this conference:

10x Genomics
Please stop by to meet these exhibitors during the conference.


We gratefully acknowledge additional support for this conference from:

Integra Foundation

We gratefully acknowledge additional in-kind support for this conference from those foregoing speaker expense reimbursements:



Genentech, Inc.


We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:


Click here to view more of these organizations


Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:


Click here to view more of these organizations


If your organization is interested in joining these entities in support of Keystone Symposia, please contact: Sarah Lavicka, Director of Development, Email: sarahl@keystonesymposia.org,
Phone:+1 970-262-2690

Click here for more information on Industry Support and Recognition Opportunities.

If you are interested in becoming an advertising/marketing in-kind partner, please contact:
Yvonne Psaila, Director, Marketing and Communications, Email: yvonnep@keystonesymposia.org,
Phone:+1 970-262-2676