Fairmont Banff Springs Floorplan

Registered Attendees


Registered attendees (and speakers, organizers, etc.) will have access to the following items from their Account page:

  • Abstracts from speakers and poster sessions, including the joint meeting abstracts, available 30 days prior to the meeting (You can edit your own abstract from My Account page as well)

    NOTE: Abstract authors/submitters may choose to not have their abstract available online and in the secure mobile app until a week before the meeting.

  • Full participant list, including joint meeting participants
  • Printable Invoices and Invitation Letters
  • Scholarship Information
  • Lodging Information

Login to My Account page

Cancer Evolution and Combinatorial Cancer Therapies: Concepts and Challenges (L1)

Scientific Organizers: William Sellers, Charles Swanton and Lillian Siu


January 19—23, 2020

Fairmont Banff Springs, Banff, AB, Canada


Sponsored by BioLegend, Inc., Incyte Corporation, Novartis Institutes for BioMedical Research and Roche


IT’S NOT TOO LATE TO SUBMIT YOUR ABSTRACT. Abstracts received can no longer be considered for short talks. Abstracts for poster display opportunities will be accepted until 6 weeks before meeting start date midnight MST.
BEWARE of booking lodging through companies unaffiliated with Keystone Symposia. Click here for more details.

Keystone Symposia is committed to maintaining a positive and respectful environment at its meetings. To this end, please review and comply with our policies.

DEADLINES:
*All deadlines end at 11:59 PM US Mountain Standard Time
Scholarship Deadline: Sep 25, 2019 [details]
Discounted Abstract Deadline: Sep 25, 2019 [details]
Abstract Deadline: Oct 17, 2019 [details]
Discounted Registration Deadline: Nov 20, 2019 [details]

Click here to view Cancellation Policy

Submit an Abstract Register Yourself Deadlines and Fees

Rates and Deadlines listed below are for the 2020-L1 "Cancer Evolution and Combinatorial Cancer Therapies: Concepts and Challenges" conference only.

*All deadlines end at 11:59 PM US Mountain Standard Time

Deadline Date Cost
Discounted Abstract Deadline
More details
Before and On September 25, 2019 100.00 USD*
- 50.00 USD discount
Abstract Deadline
More details
After September 25, 2019 until December 8, 2019 100.00 USD*
* 50.00 USD of Abstract fee deducted from your registration fee when you register for this meeting
Scholarship
More details
September 25, 2019 n/a
Discounted NON-STUDENT Registration
More details
Before and On November 20, 2019 945.00 USD
(includes 200.00 discount)
Regular NON-STUDENT Registration
More details
After November 20, 2019 1145.00 USD
Discounted STUDENT Registration
More details
Before and On November 20, 2019 720.00 USD
(includes 200.00 discount)
Regular STUDENT Registration
More details
After November 20, 2019 920.00 USD

* Changes in payment type that result in a refund are subject to a processing fee.
* Currency exchange gains/losses are the responsibility of the registrant and the Keystone Symposia will accept no liability for money loss through bank charges, transfers or currency fluctuations.




Discounted Abstract Deadline: September 25, 2019

*All deadlines end at 11:59 PM US Mountain Standard Time

Abstract Submission Fee: 100.00 USD*
Submission by this date receives 50.00 USD discount.
*50.00 USD will be applied to Registration Fee when you register

Abstract Details: It is best to submit your abstract early. Abstract and registration spaces are limited and may fill prior to the abstract or discounted registration deadlines. Submitting an abstract does not constitute or guarantee registration.

Submitting your abstract early allows us to:
  • submit your abstract to organizers to be considered for a short talk
  • accept your abstract online
  • include your abstract on our website and in our secure mobile app
  • reserve your space at the meeting for a poster presentation.**
**Submitting an abstract does not constitute or guarantee registration.
(The Abstract Deadline: is October 17, 2019)

Global Health Travel Award Deadline:

*All deadlines end at 11:59 PM US Mountain Standard Time


Global Health Travel Award Details: You MUST complete your Global Health Travel Award appplication by the Global Health Travel Award Deadline and complete the other required steps (verify your contact information and submit a recommendation letter) to be considered for a travel award.


Click here to learn more about Global Health Travel Awards.

Scholarship Deadline: September 25, 2019

*All deadlines end at 11:59 PM US Mountain Standard Time


Scholarship Details: You MUST submit your abstract by the Scholarship Deadline and complete the other required steps (submit a scholarship application and submit a mentor letter) to be considered for a scholarship.

Click here to learn more about Scholarships.

Abstract Deadline: October 17, 2019

*All deadlines end at 11:59 PM US Mountain Standard Time


Abstract Submission Fee: 100.00 USD*
*50.00 USD will be applied to Registration Fee when you register

Details: It is best to submit your abstract early. Abstract and registration spaces are limited and may fill prior to the abstract or discounted registration deadline. Submitting an abstract does not constitute or guarantee registration.

Submitting your abstract by the Abstract Deadline allows us to:

  • submit your abstract to organizers to be considered for a short talk
  • include your abstract on our website and in our secure mobile app
  • reserve your space at the meeting for a poster presentation.**
**Submitting an abstract does not constitute or guarantee registration.
Abstracts submitted after the Abstract Deadline will NOT be considered for a short talk.

(Discounted Abstract Deadline: is September 25, 2019)

Discounted Registration Deadline: November 20, 2019

*All deadlines end at 11:59 PM US Mountain Standard Time


Registration Fee: 945.00 USD* (includes 200.00 USD discount)
Student Registration Fee: 720.00 USD* (must complete student verification form)

*Includes 50.00 USD of your abstract submission fee

After the Discounted Registration Deadline:


Registration Fee: 1145.00 USD*
Student Registration Fee: 920.00 USD* (must complete student verification form)

*Includes 50.00 USD of your abstract submission fee

Registration spaces are limited and may fill prior to discounted registration deadline.

Please be advised that some meeting participants have received calls and emails from a number of different housing services, including "Exhibitors Housing Services," “Expo Housing Services,” "Global Housing," etc. THESE COMPANIES ARE NOT AFFILIATED WITH KEYSTONE SYMPOSIA and are not authorized by Keystone Symposia to contact you. These companies may tell you that the meeting is filling, without any actual knowledge to that effect, and pressure you into giving them your credit card number to make a lodging reservation with them.

We highly recommend that you not make a reservation with these companies or any other housing service! These companies' representations to participants have been misleading. Please report any calls or correspondence you might have received to Keystone Symposia and book only through lodging links in your Keystone Symposia account, an established travel agency or directly with the hotel(s) listed on our website.
No registration fees are used to fund entertainment or alcohol at this conference

Conference Program    Print  |   View meeting in 12 hr (am/pm) time


The meeting will begin on Sunday, January 19 with registration from 16:00 to 20:00 and a welcome mixer from 18:00 to 20:00. Conference events conclude on Thursday, January 23 with a closing plenary session from 17:00 to 19:00, followed by a social hour and entertainment. We recommend return travel on Friday, January 24 in order to fully experience the meeting.

SUNDAY, JANUARY 19

16:00—20:00
Arrival and Registration

Riverview Lounge
18:00—20:00
Welcome Mixer
No registration fees are used to fund alcohol served at this function.

Riverview Lounge

MONDAY, JANUARY 20

07:00—08:00
Breakfast

Alberta/New Brunswick
08:00—09:00
Welcome and Keynote Address
Registered attendees can view abstracts starting on 12/19/2019

Cascade Ballroom
Charles Swanton, Francis Crick Institute, UK
TRACERx: Tracking Cancer Evolution, Metastases and Immune Evasion

09:00—11:30
The Evolution of Cancer I
Registered attendees can view abstracts starting on 12/19/2019

Cascade Ballroom
Carlo Maley, Arizona State University, USA
Lessons in Cancer Prevention from Whales and Other Animals

Coffee Break

Trevor A. Graham, Queen Mary University of London, UK
Evolution of Copy Number Alterations in Colon Cancer

Andrea Sottoriva, Institute of Cancer Research, UK
Harnessing Evolutionary Steering in Cancer Therapy to Control Drug Resistance

Natalie Andersson, Lund University, Sweden
Short Talk: High-Risk Pediatric Cancer Genomes are Shaped by Intense Phylogenetic Branching Emerging at Specific Points in Evolutionary History

Floris P. Barthel, The Jackson Laboratory, USA
Short Talk: Longitudinal Molecular Trajectories of Diffuse Glioma in Adults

11:30—17:00
On Own for Lunch

11:30—13:00
Poster Setup

Alberta/New Brunswick
13:00—22:00
Poster Viewing

Alberta/New Brunswick
16:30—17:00
Coffee Available

Riverview Lounge
17:00—19:00
The Evolution of Cancer II
Registered attendees can view abstracts starting on 12/19/2019

Cascade Ballroom
Samra Turajlic, Royal Marsden Hospital, UK
Tracking Cancer Evolution Reveals Constrained Routes to Metastases: TRACERx Renal

Giovanni Ciriello, University of Lausanne, Switzerland
Conditional Selection of Genomic Alterations Dictates Cancer Evolution and Oncogenic Dependencies

Christina Curtis, Stanford University, USA
Towards Quantifying and Forecasting Tumor Progression

Sarah J. Aitken, University of Cambridge, UK
Short Talk: Pervasive Segregation of DNA Lesions Generates Genetic Diversity in Cancer

James R. Torpy, Garvan Institute of Medical Research, Australia
Short Talk: Copy Number Variation Profiles Derived from Single Cell RNA-Sequencing Data Reveals Diverse Intra-Tumour Heterogeneity across Multiple Breast Cancer Subtypes

19:00—20:00
Social Hour with Lite Bites
No registration fees are used to fund alcohol served at this function.

Alberta/New Brunswick
19:30—22:00
Poster Session 1

Alberta/New Brunswick

TUESDAY, JANUARY 21

07:00—08:00
Breakfast

Alberta/New Brunswick
08:00—11:15
Cancer Heterogeneity
Registered attendees can view abstracts starting on 12/19/2019

Cascade Ballroom
Sorana Morrissy, University of Calgary, Canada
Tracking Intra-Tumor Heterogeneity in Brain Tumors

Jeffrey A. Engelman, Novartis Institutes for BioMedical Research, USA
The Therapeutic Implications for Cancer Heterogeneity

Coffee Break

Sohrab Shah, Memorial Sloan Kettering Cancer Center, USA
Clonal Genotype and Population Structure Inference from Single-Cell Tumor Sequencing

Thomas G. Graeber, University of California, Los Angeles, USA
Pan-Cancer Convergence to a Small-Cell Neuroendocrine Phenotype that Shares Susceptibilities with Hematological Malignancies

Anneleen Daemen, ORIC Pharmaceuticals, USA
Short Talk: Transcriptional Subtypes Resolve Tumor Heterogeneity and Identify Therapeutic Vulnerabilities in Lung Cancer

David Gisselsson Nord, Lund University, Sweden
Short Talk: Complex Clonal Dynamics under Therapy in Neuroblastoma Reflect a Simple Phylogenetic Hierarchy of Single Cells

Hunter Shain, University of California San Francisco, USA
Short Talk: The Genetic Evolution of Metastatic Uveal Melanoma

11:15—17:00
On Own for Lunch

11:15—13:00
Poster Setup

Alberta/New Brunswick
13:00—22:00
Poster Viewing

Alberta/New Brunswick
16:30—17:00
Coffee Available

Riverview Lounge
17:00—19:00
Understanding Checkpoints and Resistance in Immuno-Oncology
Registered attendees can view abstracts starting on 12/19/2019

Cascade Ballroom
Marios Giannakis, Dana-Farber Cancer Institute, USA
Identification of Modulators of Immune Response from the Clinic: Implications for Combining I/O Agents

Elisabeth G.E. de Vries, Universitair Medisch Centrum Groningen, Netherlands
Molecular Imaging for Immunotherapy

Benjamin D. Greenbaum, Icahn School of Medicine at Mount Sinai, USA
Modeling the Emergence and Evolution of Non-Self in Tumors

Ashley DiMarco, Duke University, USA
Short Talk: APOBEC Mutagenesis as a Driver of Tumor Evolution through Tumor Cell-Intrinsic Mechanisms and by Modulating Tumor-Immune System Interactions

Fernando Souza-Fonseca-Guimaraes, University of Queensland, Australia
Short Talk: Therapeutic Blockade of TGF-β Superfamily Members Improves NK Cell Function and Anti-Tumor Immunity

19:00—20:00
Social Hour with Lite Bites
No registration fees are used to fund alcohol served at this function.

Alberta/New Brunswick
19:30—22:00
Poster Session 2

Alberta/New Brunswick

WEDNESDAY, JANUARY 22

07:00—08:00
Breakfast

Alberta/New Brunswick
08:00—11:00
Leveraging Therapeutic Resistance towards Combination Therapies
Registered attendees can view abstracts starting on 12/19/2019

Cascade Ballroom
Poulikos I. Poulikakos, Icahn School of Medicine at Mount Sinai, USA
Resistance to CDK Inhibitors

Gaddy Getz, Broad Institute, USA
The Elucidation of Drivers of Therapeutic Resistant from Large-Scale Patient Sample Analysis

Coffee Break

Alice T. Shaw, Massachusetts General Hospital Cancer Center, USA
Understanding and Overcoming Resistance to ALK Inhibitors in NSCLC

Himisha Beltran, Dana Farber Cancer Institute, USA
Therapeutic Resistance to Androgen Receptor Blockade

Matthew J. Martin, AstraZeneca, UK
Short Talk: Eliminating Osimertinib Drug Tolerant Persister Cells Via Activation of the Extrinsic Apoptosis Pathway

Sean Misek, Michigan State University, USA
Short Talk: Identification of Pharmacological Vulnerabilities in BRAFi-Resistant Melanoma

11:00—17:00
On Own for Lunch

11:00—13:00
Poster Setup

Alberta/New Brunswick
13:00—22:00
Poster Viewing

Alberta/New Brunswick
16:30—17:00
Coffee Available

Riverview Lounge
17:00—19:00
The Preclinical Modeling and Discovery of Combinations
Registered attendees can view abstracts starting on 12/19/2019

Cascade Ballroom
William R. Sellers, Broad Institute of MIT and Harvard, USA
Targeting Genetic Redundancy in Cancer through Combinatorial CRISPR Screens

Jonathan S. Weissman, University of California, San Francisco, USA
Single-cell-resolution Lineage Tracing of Tumors in a Mouse Xenograft Model Reveals Rapid and Multidirectional Metastasis

Peter Sorger, Harvard Medical School, USA
Measuring and Modeling Cancer Combination Therapy in Preclinical Models and Patient Populations

Kasey L. Couts, University of Colorado Denver, USA
Short Talk: Loss of Innate Immune Sensing Contributes to Mucosal Melanoma Development and Immunotherapy Resistance

Sophia Wild, University of Cambridge, UK
Short Talk: ClonEx-Seq: Characterising Clonal Evolution in Time and Space with a Toolkit of Expressable Barcodes

19:00—20:00
Social Hour with Lite Bites
No registration fees are used to fund alcohol served at this function.

Alberta/New Brunswick
19:30—22:00
Poster Session 3

Alberta/New Brunswick

THURSDAY, JANUARY 23

07:00—08:00
Breakfast

Alberta/New Brunswick
08:00—11:00
Therapeutic Combinations
Registered attendees can view abstracts starting on 12/19/2019

Cascade Ballroom
Speaker to be Announced

Lillian Siu, Princess Margaret Hospital, Canada
Oncology Drug Combinations - Are We at an Impasse?

Coffee Break

Steven Stein, Incyte, USA
The Development of IO Combinations

Shumei Kato, University of California, San Diego Moores Cancer Center, USA
Talk Title to be Announced

Akash Mitra, University of Texas MD Anderson Cancer Center, USA
Short Talk: Immune Enrichment and T-Cell Receptor (TCR) Frequencies Predict Response to Immune Checkpoint Blockade (ICB) in Sarcoma

Anna Vilgelm, Ohio State University, USA
Short Talk: Combination Treatment with MDM2 Antagonist Overcomes Intrinsic Resistance to CDK4/6 Inhibition

11:00—17:00
On Own for Lunch

16:30—17:00
Coffee Available

Riverview Lounge
17:00—18:45
Clinical Trials and Clinical Trial Design
Registered attendees can view abstracts starting on 12/19/2019

Cascade Ballroom
Tatiana Prowell, Food and Drug Administration and Johns Hopkins University, USA
The Regulatory View on the Development of Combination Therapeutics

Jeanne Tie, Peter MacCallum Cancer Centre / Walter & Eliza Hall Institute, Australia
Can Circulating Tumor DNA Re-Define the Adjuvant Treatment Paradigm?

Antoni Ribas, University of California, Los Angeles, USA
Testing I/O Combinations in Clinical Trials

18:45—19:00
Meeting Wrap-Up: Outcomes and Future Directions (Organizers)
Registered attendees can view abstracts starting on 12/19/2019

Cascade Ballroom
19:00—20:00
Social Hour with Lite Bites
No registration fees are used to fund alcohol served at this function.

Alberta/New Brunswick
20:00—23:00
Entertainment
Entertainment is not subsidized by conference registration fees nor any U.S. federal government grants. Funding for this expense is provided by other revenue sources.

Alberta/New Brunswick

FRIDAY, JANUARY 24

 
Departure


*Session Chair †Invited, not yet responded.



Keystone Symposia thanks our Sponsors for generously supporting this meeting:

BioLegend, Inc. Incyte Corporation
Novartis Institutes for BioMedical Research Roche

We gratefully acknowledge additional support from these exhibitors at this conference:

American Association for Cancer Research (AACR) Myriad-RBM
Please stop by to meet these exhibitors during the conference.


We gratefully acknowledge additional in-kind support for this conference from those foregoing speaker expense reimbursements:



Incyte Corporation


We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:


Click here to view more of these organizations


Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:


Click here to view more of these organizations


If your organization is interested in joining these entities in support of Keystone Symposia, please contact: Sarah Lavicka, Director of Corporate Relations, Email: sarahl@keystonesymposia.org,
Phone:+1 970-262-2690

Click here for more information on Industry Support and Recognition Opportunities.

If you are interested in becoming an advertising/marketing in-kind partner, please contact:
Nick Dua, Senior Director, Communications, Email: nickd@keystonesymposia.org,
Phone:+1 970-262-1179