Keystone Resort Floorplan

Registered Attendees


Registered attendees (and speakers, organizers, etc.) will have access to the following items from their Account page:

  • Abstracts from speakers and poster sessions, including the joint meeting abstracts, available 30 days prior to the meeting (You can edit your own abstract from My Account page as well)

    NOTE: Abstract authors/submitters may choose to not have their abstract available online and in the secure mobile app until a week before the meeting.

  • Full participant list, including joint meeting participants
  • Printable Invoices and Invitation Letters
  • Scholarship Information
  • Lodging Information

Login to My Account page

Hypoxia: Molecules, Mechanisms and Disease  (A3)

Scientific Organizers: José López-Barneo, Sarah R. Walmsley, Hesham A. Sadek and Jacques Pouysségur


January 19—23, 2020

Keystone Resort, Keystone, CO, USA


Sponsored by Akebia Therapeutics


IT’S NOT TOO LATE TO SUBMIT YOUR ABSTRACT. Abstracts received can no longer be considered for short talks. Abstracts for poster display opportunities will be accepted until 6 weeks before meeting start date midnight MST.
BEWARE of booking lodging through companies unaffiliated with Keystone Symposia. Click here for more details.

Keystone Symposia is committed to maintaining a positive and respectful environment at its meetings. To this end, please review and comply with our policies.

DEADLINES:
*All deadlines end at 11:59 PM US Mountain Standard Time
Scholarship Deadline: Sep 25, 2019 [details]
Discounted Abstract Deadline: Sep 25, 2019 [details]
Abstract Deadline: Oct 16, 2019 [details]
Discounted Registration Deadline: Nov 19, 2019 [details]

Click here to view Cancellation Policy

Submit an Abstract Register Yourself Deadlines and Fees

Rates and Deadlines listed below are for the 2020-A3 "Hypoxia: Molecules, Mechanisms and Disease " conference only.

*All deadlines end at 11:59 PM US Mountain Standard Time

Deadline Date Cost
Discounted Abstract Deadline
More details
Before and On September 25, 2019 100.00 USD*
- 50.00 USD discount
Abstract Deadline
More details
After September 25, 2019 until December 8, 2019 100.00 USD*
* 50.00 USD of Abstract fee deducted from your registration fee when you register for this meeting
Scholarship
More details
September 25, 2019 n/a
Discounted NON-STUDENT Registration
More details
Before and On November 19, 2019 845.00 USD
(includes 200.00 discount)
Regular NON-STUDENT Registration
More details
After November 19, 2019 1045.00 USD
Discounted STUDENT Registration
More details
Before and On November 19, 2019 620.00 USD
(includes 200.00 discount)
Regular STUDENT Registration
More details
After November 19, 2019 820.00 USD

* Changes in payment type that result in a refund are subject to a processing fee.
* Currency exchange gains/losses are the responsibility of the registrant and the Keystone Symposia will accept no liability for money loss through bank charges, transfers or currency fluctuations.




Discounted Abstract Deadline: September 25, 2019

*All deadlines end at 11:59 PM US Mountain Standard Time

Abstract Submission Fee: 100.00 USD*
Submission by this date receives 50.00 USD discount.
*50.00 USD will be applied to Registration Fee when you register

Abstract Details: It is best to submit your abstract early. Abstract and registration spaces are limited and may fill prior to the abstract or discounted registration deadlines. Submitting an abstract does not constitute or guarantee registration.

Submitting your abstract early allows us to:
  • submit your abstract to organizers to be considered for a short talk
  • accept your abstract online
  • include your abstract on our website and in our secure mobile app
  • reserve your space at the meeting for a poster presentation.**
**Submitting an abstract does not constitute or guarantee registration.
(The Abstract Deadline: is October 16, 2019)

Global Health Travel Award Deadline:

*All deadlines end at 11:59 PM US Mountain Standard Time


Global Health Travel Award Details: You MUST complete your Global Health Travel Award appplication by the Global Health Travel Award Deadline and complete the other required steps (verify your contact information and submit a recommendation letter) to be considered for a travel award.


Click here to learn more about Global Health Travel Awards.

Scholarship Deadline: September 25, 2019

*All deadlines end at 11:59 PM US Mountain Standard Time


Scholarship Details: You MUST submit your abstract by the Scholarship Deadline and complete the other required steps (submit a scholarship application and submit a mentor letter) to be considered for a scholarship.

Click here to learn more about Scholarships.

Abstract Deadline: October 16, 2019

*All deadlines end at 11:59 PM US Mountain Standard Time


Abstract Submission Fee: 100.00 USD*
*50.00 USD will be applied to Registration Fee when you register

Details: It is best to submit your abstract early. Abstract and registration spaces are limited and may fill prior to the abstract or discounted registration deadline. Submitting an abstract does not constitute or guarantee registration.

Submitting your abstract by the Abstract Deadline allows us to:

  • submit your abstract to organizers to be considered for a short talk
  • include your abstract on our website and in our secure mobile app
  • reserve your space at the meeting for a poster presentation.**
**Submitting an abstract does not constitute or guarantee registration.
Abstracts submitted after the Abstract Deadline will NOT be considered for a short talk.

(Discounted Abstract Deadline: is September 25, 2019)

Discounted Registration Deadline: November 19, 2019

*All deadlines end at 11:59 PM US Mountain Standard Time


Registration Fee: 845.00 USD* (includes 200.00 USD discount)
Student Registration Fee: 620.00 USD* (must complete student verification form)

*Includes 50.00 USD of your abstract submission fee

After the Discounted Registration Deadline:


Registration Fee: 1045.00 USD*
Student Registration Fee: 820.00 USD* (must complete student verification form)

*Includes 50.00 USD of your abstract submission fee

Registration spaces are limited and may fill prior to discounted registration deadline.

Please be advised that some meeting participants have received calls and emails from a number of different housing services, including "Exhibitors Housing Services," “Expo Housing Services,” "Global Housing," etc. THESE COMPANIES ARE NOT AFFILIATED WITH KEYSTONE SYMPOSIA and are not authorized by Keystone Symposia to contact you. These companies may tell you that the meeting is filling, without any actual knowledge to that effect, and pressure you into giving them your credit card number to make a lodging reservation with them.

We highly recommend that you not make a reservation with these companies or any other housing service! These companies' representations to participants have been misleading. Please report any calls or correspondence you might have received to Keystone Symposia and book only through lodging links in your Keystone Symposia account, an established travel agency or directly with the hotel(s) listed on our website.
No registration fees are used to fund entertainment or alcohol at this conference

Conference Program    Print  |   View meeting in 24 hr (international) time


The meeting will begin on Sunday, January 19 with registration from 16:00 to 20:00 and a welcome mixer from 18:00 to 20:00. Conference events conclude on Thursday, January 23 with a closing plenary session from 17:00 to 19:00, followed by a social hour and entertainment. We recommend return travel on Friday, January 24 in order to fully experience the meeting.

SUNDAY, JANUARY 19

4:00—8:00 PM
Arrival and Registration

Longs Peak Foyer
6:00—8:00 PM
Welcome Mixer
No registration fees are used to fund alcohol served at this function.

Longs Peak Foyer

MONDAY, JANUARY 20

7:00—8:00 AM
Breakfast

Longs/Quandary Peaks
8:00—9:00 AM
Keynote Address
Registered attendees can view abstracts starting on 12/19/2019

Grays Peak
Randall S. Johnson, University of Cambridge, UK
Hypoxic response is not pathological: oxygen flux, physiology, and HIF

9:00—11:15 AM
Hypoxia Signaling: Acute Oxygen Sensing
Registered attendees can view abstracts starting on 12/19/2019

Grays Peak
José López-Barneo, University of Seville, Spain
Acute Oxygen Sensing by Arterial Chemoreceptors: A Mix of Metabolism, Mitochondrial Signaling and Ion Channels

Coffee Break

Alexander Gourine, University College London, UK
Acute Oxygen Sensing in the Brain

Natascha Sommer, Justus Liebig University, Germany
Oxygen Sensing in the Lung Vasculature: Role in Pulmonary Hypertension

Emma J. Hodson, Francis Crick Institute, UK
Short Talk: HIF-2α in the Carotid Body

11:15 AM—5:00 PM
On Own for Lunch

11:15 AM—1:00 PM
Poster Setup

Longs/Quandary Peaks
1:00—10:00 PM
Poster Viewing

Longs/Quandary Peaks
4:30—5:00 PM
Coffee Available

Longs Peak Foyer
5:00—7:00 PM
Pathophysiology of Hypoxia and Ischemia
Registered attendees can view abstracts starting on 12/19/2019

Grays Peak
Thomas Park, University of Illinois at Chicago, USA
Mechanisms of Extreme Tolerance to Anoxia in the African Naked Mole-Rat

Silvia V. Conde, CEDOC- Centro de Estudos de Doenças Crónicas, Portugal
Novel Therapies in Carotid Body-Mediated Sympathetic Over-Activation Syndromes

Jennifer V.F. Potter, University of Virginia, USA
Pharmacology of Peripheral and Central Chemoreceptors: The Respiratory Depression and Opioid Epidemics

Jong Park, University of Maryland, Baltimore County, USA
Short Talk: Role of Lactate-NDRG1 Signaling in Low Oxygen Tolerance

Nathaniel Berg, University of Texas Health Science Center at Houston, USA
Short Talk: Hif1a-Dependent Expression of miR-147 in Myeloid Cells Promotes Resolution of Acute Lung Injury

7:00—8:00 PM
Social Hour with Lite Bites
No registration fees are used to fund alcohol served at this function.

Longs/Quandary Peaks
7:30—10:00 PM
Poster Session 1

Longs/Quandary Peaks

TUESDAY, JANUARY 21

7:00—8:00 AM
Breakfast

Longs/Quandary Peaks
8:00—8:20 AM
Special Session: Tribute to William G. Kaelin, Peter J. Ratcliffe and Gregg L. Semenza (2019 Nobel Laureates)
Registered attendees can view abstracts starting on 12/19/2019

8:20—11:30 AM
Hypoxia Signaling: Hydroxylases and the Hypoxia Inducible Factors
Registered attendees can view abstracts starting on 12/19/2019

Grays Peak
Peter J. Ratcliffe, University of Oxford, UK
Regulation of the PHD/HIF Hypoxic Response

Joseph A. Garcia, Columbia University Medical Center, USA
An Acetate Switch Links Dynamic Changes in Intermediary Metabolism with Stress Signaling by HIF-2 in Mammals

Coffee Break

William G. Kaelin, Jr., Dana-Farber Cancer Institute, USA
New Therapeutic Strategies Based on the Functions of the VHL Tumor Suppressor and HIF

Erquan Zhang, National Institute of Biological Sciences, China
Towards Understanding the Mutual Regulation of Hypoxia Signaling and the Circadian Clock

Stephanie Naas, Universitätsklinikum Erlangen, Germany
Short Talk: Transcriptional Auto-Regulation of Hypoxia-Inducible Factor-2α in Renal Cells

Brian M W Ortmann†, University of Cambridge, UK
Short Talk: How is the Hypoxia Inducible Factor Response Efficiently Activated?

11:30 AM—5:00 PM
On Own for Lunch

11:30 AM—1:00 PM
Poster Setup

Longs/Quandary Peaks
1:00—10:00 PM
Poster Viewing

Longs/Quandary Peaks
3:00—4:30 PM
Workshop 1

Grays Peak
Alejandro Moreno†, Instituto de Biomedicina de Sevilla, Spain
Acute Oxygen Sensing by Ca2+ Channels in Vascular Smooth Muscle Depends on Mitochondrial Complex I Signaling

Andrew Cowburn, Imperial College London, UK
Targeting HIF2α Hetero-Dimerisation as a Novel Therapeutic Strategy for PAH

Mariia Burdyniuk, Stanford University, USA
Human 3D Cellular Model of Hypoxic Brain Injury of Prematurity: Alterations in GABAergic Interneurons

Andreas Bapst, Universität Zürich, Switzerland
Telopode Function in Cell Lines Derived from Erythropoietin-Tagged Mouse Kidney Telocytes

Josef Prchal, University of Utah, USA
Augmented HIF and Thrombosis

Charandeep Singh, Cleveland Clinic, USA
Is Metabolism in Hyperoxia Opposite to That in Hypoxia?

4:30—5:00 PM
Coffee Available

Longs Peak Foyer
5:00—7:00 PM
Redox Signaling in Hypoxia Responses
Registered attendees can view abstracts starting on 12/19/2019

Grays Peak
Paul T. Schumacker, Northwestern University, USA
Role of Mitochondria in Regulation of Cell Stress Responses

Vamsi K. Mootha, Massachusetts General Hospital, USA
Hypoxia in Mitochondrial Disease

Agnes Görlach, German Heart Center Munich, TU Munich, Germany
Hypoxia and ROS Crosstalk in Programming of Cardiovascular Diseases

Margaret Ashcroft†, University of Cambridge, UK
Short Talk: The Redox-Regulated Disulphide Relay System Controls Hypoxia Responses

Hanako Kobayashi, Vanderbilt University, USA
Short Talk: HIF Activation in TFAM-Deficient Tubular Epithelium Mitigates Renal Cyst Development

7:00—7:15 PM
Celebratory Toast to Nobel Prize
Registered attendees can view abstracts starting on 12/19/2019

7:15—8:15 PM
Social Hour with Lite Bites
No registration fees are used to fund alcohol served at this function.

Longs/Quandary Peaks
7:30—10:00 PM
Poster Session 2

Longs/Quandary Peaks

WEDNESDAY, JANUARY 22

7:00—8:00 AM
Breakfast

Longs/Quandary Peaks
8:00—11:00 AM
Hypoxia and Cancer
Registered attendees can view abstracts starting on 12/19/2019

Grays Peak
Gregg L. Semenza, Johns Hopkins University School of Medicine, USA
HIFs: Executors of the Lethal Cancer Phenotype

Fatima Mechta-Grigoriou, Curie Research Institute, France
Role of Chronic Oxidative Stress in Cancer Development

Coffee Break

Jacques Pouysségur, University of Nice, France
Exploiting Acidic, Nutrient and Oxidative Stresses in Hypoxic Tumors

Silvia Pastorekova, Biomedical Research Center, Slovak Academy of Sciences, Slovakia
Hypoxia-Induced Carbonic Anhydrase IX: Contribution to Cancer Hallmarks and Clinical Prospects

Dana Piovesan, Arcus Biosciences Inc., USA
Short Talk: Selective Inhibition of Hypoxia-Inducible Factor (HIF)-2α for Cancer

Tatsuya Suwa, Kyoto University, Japan
Short Talk: A Novel Hypoxia-Inducible Secretory Protein, HISP2, Causes Radioresistance of Hypoxic Cancer Cells in a Paracrine Manner

11:00 AM—5:00 PM
On Own for Lunch

11:00 AM—1:00 PM
Poster Setup

Longs/Quandary Peaks
1:00—10:00 PM
Poster Viewing

Longs/Quandary Peaks
3:00—4:30 PM
Workshop 2

Grays Peak
Kathryn Jaques Schunke†, University of Hawaii, USA
Regulation of HIF-1 by Chromatin Reader Protein Kinase C Binding Protein 1 (PRKCBP1)

Zachary Bacigalupa, Vanderbilt University Medical Center, USA
Targeting ACSS2 Inhibits HIF-2α Signaling and Oxidative Metabolism in ccRCC and Promotes Favorable Properties in CD4+ T Cells

Carsten C. Scholz†, University of Zürich, Switzerland
FIH-Mediated Oxygen-Dependent Regulation of the Deubiquitinase OTUB1

Violaine Sée†, University of Liverpool, UK
Identification and Characterisation of Novel Post-Translational Modifications Regulating the Hypoxia Inducible Factors, HIF-1α and HIF-2α

Ben Wielockx, Technical University of Dresden, Germany
HIF2α Is a Direct Regulator of Neutrophil Motility

Luis del Peso†, Universidad Autonoma, Spain
Metabolic Labelling of RNA Uncovers the Contribution of Transcription and Decay Rates on Hypoxia-Induced Changes in RNA Levels

4:30—5:00 PM
Coffee Available

Longs Peak Foyer
5:00—7:00 PM
New Trends and Techniques in Hypoxia Research
Registered attendees can view abstracts starting on 12/19/2019

Grays Peak
Joel A. Spencer, University of California Merced, USA
Direct Oxygen Sensing in the Bone Marrow by Two-photon Phosphorescence Lifetime Quenching

Sonia Rocha, University of Liverpool, UK
Chromatin Senses Oxygen Changes

Elaine Pinheiro, Merck Research Laboratories, USA
HIF 2alpha Inhibitors: Applications and Current Clinical Trials

F. Aisha Chow, FibroGen Inc., USA
Short Talk: Roxadustat Enhances Degradation of 3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase (HMGCR) in a HIF and INSIG Dependent Manner

Tom Keeley, University of Oxford, UK
Short Talk: Rapid Regulation of Protein Stability by 2-Aminoethanethiol Dioxygenase and the N-Degron Pathway

7:00—8:00 PM
Social Hour with Lite Bites
No registration fees are used to fund alcohol served at this function.

Longs/Quandary Peaks
7:30—10:00 PM
Poster Session 3

Longs/Quandary Peaks

THURSDAY, JANUARY 23

7:00—8:00 AM
Breakfast

Longs/Quandary Peaks
8:00—11:00 AM
Hypoxia in Stem Cells, Cell Reprogramming, and Regeneration
Registered attendees can view abstracts starting on 12/19/2019

Grays Peak
Yoshinori Yoshida, Center for iPS Cell Research and Application, Kyoto University, Japan
Hypoxia in Cell Reprogramming and Differentiation

Michaela Frye, Deutsches Krebsforschungszentrum, Germany
Post-Transcriptional Modifications in Development and Stem Cells

Coffee Break

Hesham A. Sadek, University of Texas Southwestern Medical Center, USA
Role of Hypoxia in Cardiac Regeneration

Silvia Martin-Puig, Fundación Centro Nacional de Investigaciones Cardiovasculares, Spain
Hypoxia, Cardiac Development and Disease

Yoshifumi Miyawaki†, Kyoto University Graduate School of Medicine Medical Innovation Center, Japan
Short Talk: Novel Experimental Models for VHL Disease by Using Patient-Derived Induced Pluripotent Stem Cells

Tapio Röning, University of Oulu, Finland
Short Talk: Activation of Hypoxia Response Protects Against Age-Induced Cardiac Hypertrophy

11:00 AM—5:00 PM
On Own for Lunch

4:30—5:00 PM
Coffee Available

Longs Peak Foyer
5:00—6:45 PM
Hypoxia and Inflammation
Registered attendees can view abstracts starting on 12/19/2019

Grays Peak
Sarah R. Walmsley, University of Edinburgh, Queen's Medical Research Institute, UK
Hypoxic Reprogramming of Neutrophil Metabolism

Cormac Taylor, University College Dublin, Ireland
Hypoxia, Immunity and Inflammation

Alberto Pascual, Instituto de Biomedicina de Sevilla, Spain
Hypoxia, Microglia, and Endothelial Cells in Alzheimer’s Disease Pathogenesis

Laura Barbieri, Karolinska Institutet, Sweden
Short Talk: Lactate Is an Alternative Fuel for Cytotoxic CD8+ T Cells

6:45—7:00 PM
Meeting Wrap-Up: Outcomes and Future Directions (Organizers)
Registered attendees can view abstracts starting on 12/19/2019

Grays Peak
7:00—8:00 PM
Social Hour with Lite Bites
No registration fees are used to fund alcohol served at this function.

Longs/Quandary Peaks
8:00—11:00 PM
Entertainment
Entertainment is not subsidized by conference registration fees nor any U.S. federal government grants. Funding for this expense is provided by other revenue sources.

Longs/Quandary Peaks

FRIDAY, JANUARY 24

 
Departure


*Session Chair †Invited, not yet responded.



Keystone Symposia thanks our Sponsor for generously supporting this meeting:

Akebia Therapeutics

We gratefully acknowledge additional support from these exhibitors at this conference:

Baker Ruskinn Don Whitley Scientific Limited
HypOxygen
 
Please stop by to meet these exhibitors during the conference.


We gratefully acknowledge the generous grant for this conference provided by:


National Institutes of Health

Grant No. 1R13HL149442-01

Funding for this conference was made possible (in part) by 1R13HL149442-01 from the National Institutes of Health. The views expressed in written conference materials or publications and by speakers and moderators do not necessarily reflect the official policies of the Department of Health and Human Services; nor does mention by trade names, commercial practices, or organizations imply endorsement by the U.S. Government.


We gratefully acknowledge additional support for this conference from:

Bio-Techne

We gratefully acknowledge additional in-kind support for this conference from those foregoing speaker expense reimbursements:



Merck Research Laboratories


We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:


Click here to view more of these organizations


Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:


Click here to view more of these organizations


If your organization is interested in joining these entities in support of Keystone Symposia, please contact: Sarah Lavicka, Director of Corporate Relations, Email: sarahl@keystonesymposia.org,
Phone:+1 970-262-2690

Click here for more information on Industry Support and Recognition Opportunities.

If you are interested in becoming an advertising/marketing in-kind partner, please contact:
Nick Dua, Senior Director, Communications, Email: nickd@keystonesymposia.org,
Phone:+1 970-262-1179